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KMID : 0861019970120020131
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Korea Journal of Herbology
1997 Volume.12 No. 2 p.131 ~ p.141
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RHIZOMA SAURURI (RS) induced the Morphological Change of the Peritoneal Macrophages through Nitric Oxide (NO)
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秦尙佑/Jin, Sang-Woo
朴星珠/辛民敎/宋昊埈/Park, Seong-Ju/Shin, Min-Kyo/Song, Ho-Joon
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Abstract
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RIZOMA SAURURI (RS) has been known to use antiinflammatory drug. To investigated the mechinism of RS-induced Peritoneal Macrophage activation, I examineded the ability of morphological change of Peritoneal Macrophages by RS. RS alone had only a small effect, whereas in combination with rIFN-γ markedly increased NO synthesis in a dose dependent manner.
RS potently increased TNF-α secretion in Peritoneal Macrophages. In conclusion, RS induced the morphological change of the Peritoneal Macrophages through NO.
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